真空冷冻干燥方案解决专家 Expert in vacuum freeze drying solutions

Foring Science Instrument Technology Development(Beijing) Co.,Ltd. Four Ring Science Instrument Technology Development(Hebei) Co., Ltd.

Company Brief

Foring Science Instrument Technology Development (Bejing) Co.,Ltd. is headed by the former technical R&D and management director of Beijing Sihuan Scientific Instrument Factory Co., Ltd. It is a service provider that provides customers with professional vacuum freeze-drying equipment and solutions. We adhere to the service concept of "customer-centric, pursuing higher customer satisfaction", personalized service, innovative design, efficient processing, quality assurance, and can provide and design single or multiple freeze-drying equipment supportingsystemsthatmeetGMPstandards according touserneeds,suchasnegative pressure and sterile isolators, automatic loading and unloading,and external CiP systems.

The company's equipment production has passed the ISO quality management system certification and theEUCEcertification,and haswon1provincial and ministerial level science andtechnologyprogresssecondprizeandmultiplepatents.

We willbe based on the win-win development, deepen technology, pursue excellence and continuetoinnovate.

Four Ring Science Instrument Technology Development ( Hebei ） Co., Ltd. is the only authorized manufacturer.

四环冻干

Corporate Purpose Excellence Responsibility

Entrepreneurial spirit

Respect trust responsibilitymutual benefit

Enterprise core values

Excellent and effective talent strategy Safe and reliableproductquality Pursueperfectwork standards

Enterprise service concept

Customer-centric Pursue higher customer satisfaction

Our advantages

Personalized service:

Professionalcommunication,scientific analysis,and precise equipment solutions based onuserneeds and material characteristics.

Innovative design:

Demand driven, high configuration, compact structure, simple operation and maintenance.

Efficient processing:

Digital full-process control, system optimization, material freeze-drying effciency.

Quality assurance:

Fast and high-quality life cycle services to ensure stable,reliable and safe operation of products.

Product feature:

·The equipment production has passed ISO quality management system certification and EU CE certification.
Compact design,easy to maintain and operate;
Wecan customizevacuum freeze drying equipment and supporting solutions for customers, and select equipment functions and component sizes according to different needs; Equipmentcomponentswereusedfromwell-known domestic and foreignbrand. The surface treatmentof mechanical parts exceeds the relevant national and industry regulations;
All interfacesusestandard flangesforquick installation.
Thecontrol systemwithfriendlyinterface,remote monitoring and inspection maintenance,supports the constructionofbigdataandsmartlaboratories.
Equipmentcomponentsareequippedwithvarious sensorsto accuratelycontrol the equipment,immediately alarmwhenabnormaloperationoccurs,andactively protect the operation.
Speciallydesignedgland and automaticvacuum adjustmentdevicespreventmaterial contamination,ensure accuratecontrolofvacuumdegree. Thepilot equipment is designed and manufactured in accordancewith the national pharmaceutical machinery industry standards,provide a detailed process data for future production. The after-sales service system in accordance with the highest national standard.

Quality Control

Our quality concept is rooted in the rigorous pursuit of quality in military medical research. Based on the system quality control concept, we use quality planning, generation, control, inspection and assurance technology to steadily improve product quality. The quality control of the production process is strictly managed in accordance with the ISO system. The quality of the production link is traceable. The equipment is fully tested before leaving the factoryand aqualitysystemdocument isformed.

After-sales technical support

The after-sales service system is implemented in accordance with the national five-star standard, providing customers with complete interactive technology, guarantee and management services for freeze-dryingprocessesandequipment.

We have established regional service centers in Beijing, Shanghai, Suzhou, Guangzhou, Hangzhou, Nanjing, Xi'an, Chengdu, Wuhan, Zhengzhou, Shenzhen, etc., and have service points in major provincial capitals. We have established a customer service system that radiates across the country. We have a professional, efficient and responsive customer service and technical support team that canassistusersinbuildingatechnicaldatasysteminaccordancewithnationalandindustry-related standardsandrequirements,andimprovethelevelofproductuseandmaintenance.

(Take over the after-sales and technical services of the original Beijing Sihuan Scientific Instrument Factory Co., Ltd., and provide a full range of accessories for all types of products within nine years).

Technical advantages

Control System

The control system consists of programmable controlers, human-machine interface devices, sensors, terminal relays, digital-to-analog conversion and other modules. Industrial-grade intelligent control software controls the equipment process, detects the system's operating status, and displays alarm points and operating conditions in real time.

· Adjust freeze-drying parameters according to management authority. The whole freeze-drying process is programmed and automatically controlled. Customers only need to adjust the freeze-drying process data to form a freeze-drying process suitable for different materials. Digital password signature can store multiple fixed or custom programs for freeze-drying process management. The number of stored programs is \mathfrak{z}>=100 andeachprogramhas >=32 steps,realizing multi-level management;
·The system can automatically pre-freeze, quick-freeze and slow-freeze the materials repeatedly;
· Manual or one-button intelligent control of the entire freeze-drying process;
·The system display can be in multiple languages including Chinese and English;
· Automatically monitor, detect, record and store data related to the freeze-drying process. Data is stored and recorded once every minute (the storage recording interval is adjustable). With a USB data storage serial port, the system canbe remotely monitored, detected and maintained;
· When an abnormality occurs in the operation of equipment components during operation, the system will immediately alarm and actively protect the operation;
· Real-time display of equipment components and material temperature and vacuum degree, automatic generation of freeze-drying curve;
·The temperature and vacuum degree of the equipment are both controlled by PID;
·Vacuum and temperature calibration function;
·Freeze-drying endpoint test function;
· Host computer control;
·Online or offine eutectic point test of materials;
· The product has passed the EU CE certification, and the control system human-machine interface equipment complies with the NEMA (National Electrical Manufacturers Association) protection regulations.

Freeze Drying System

The freeze-drying systemconsists of a shelf circulation system,a freezedrying chamber, a cold trap and various pipelines and accessories to completethefreezingand heatingof thematerials.

Thefreeze-dryingchambercaneffectivelypre-freezethematerials, and the materials can be observed at any time during the freeze-drying process;
Thecontrol system accuratelycontrolstheintermediatemediumto circulate in the shelf, and the special process manufacturing process ensures that the shelf is flat and the temperature is uniform, which improves the freeze-drying efficiency;
The gas backfill system can quantitatively fill the freeze-drying chamber withprotectivegas;
The capping system can manually or electrically reliably seal the material containerin thefreeze-dryingchamberinavacuum to avoid material contamination;
Pilot freeze drying equipment can close the butterly valve of the pipeline between the freeze drying chamber and the water collection chamberbeforefreeze drying and after freeze drying to ensure that materials can be loaded and unloaded and products canbe pre-frozen inacleanenvironment;

·The cold trap is automatically defrosted.

Refrigeration system

Itconsistsofrefrigerationcompressor,condenser,expander,plateheat exchanger,oil separator,pressure controller,filter,etc.The main machine adopts imported compressor or screw machine, and the shelf and water collector are cooled by plate heat exchanger and condenser respectively. The system has redundant cooling capacity, simple design and reliable installation. The compressor uses environmentally friendly refrigerant and has multiple automatic protection functions such as over-high oil pressure, overheatingtemperatureanddelayedstart.

Vacuum system

It consists of a vacuum pump or Roots pump, a freeze-drying chamber, a vacuum gauge, pipelines and a controller. The vacuum system is redundant.

· The built-in vacuum degree is automatically and accurately adjusted during the freeze-drying process to eliminate the hidden dangers of material contamination, improve heat conduction and freezedrying efficiency, and reduce equipment and energy loss;

· Systematic vacuum testing procedures to avoid potential leaks;

· The vacuum pump is equipped with a device to prevent gas backflow, and the exhaust port is equipped with an oil mist filter to prevent the exhaust gas from polluting the surrounding environment.

Product Selection

Drying chamber device classification:

Ordinary type: suitable forfling non-standard pressure-capped containers and bulk(powder, granules, solutions) and other materials before freeze-drying.

Press-cap type: suitable for freeze-dried materials flled into vials, and sealed under vacuum after freeze-drying. Manifold type: suitable for eggplant-shaped bottles, wide-mouth bottles, external bottles, freeze-drying multiple varieties at the same time, independent control, no interference and contamination.

Rack (ampoule tube): suitable for freeze-dried materials in ampoule tubes (strains).

Optional accessories:

Multi-manifold bottle hanging device, freeze-dried bottles (eggplant-shaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, imported vacuum pump, high-speed vacuum pump oil, vacuum pump exhaust oil mist filter, vacuum pump air inlet dust filter, eutectic point tester, inert gas filling port, vial cappingmachine

Product life quality cycle

LGJ-10C/E Freeze Dryer

Technical Feature :

· The control software system is an Android system. The freeze-drying process is automatically controlled by a programmable program(optional). It canbe switched to manual operation in real time to achieve full parameter control of the freeze-drying process. During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs. It can be monitored, tested, and maintained through a remote system (optional), supporting the construction of big data and smart laboratories.

· Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage interval is adjustable), standard record 100,0o0 times, data storage capacity can be recorded for 3 years (optionall, with USB serial port for mobile data storage;

· The product production has passed the ISO quality management system and the EU CE certification, and the control system human-machine interface complies with the NEMA (National Electrical Manufacturers Association)protectionregulations.

·The system is equipped withvarious sensors to record and displayvacuum degree, cold trap temperature, material temperature,shelf temperature inreal time.Theoperationerroralarmcanprovideinstant information alarm and actively protect the operation when the temperature and pressure are abnormal during operation. Light alarm (optional);

· When the vacuum pressure of the equipment is lost at the end of the automatic freeze-drying operation or during the process, the equipment will alarm and automatically operate to protect the materials. When the temperatureof thecold trap is higher than -50°C thevacuumpumpcannotbe turned ontoprevent the entry of water vapor and affect the normal operation of the vacuum pump. It has a vacuum pump maintenance reminder function;

· The cold trap cavity and material rack are made of sanitary stainless steel. There is no coil in the cold trap, which is smooth, corrosion-resistant and easy to clean, and has the function of pre-freezing materials.

· The cold trap drying chamber is made of high-pressure and low-temperature resistant aviation organic glass material, covered with an explosion-proof film (optional), so that the entire freeze-drying process of the material canbeobserved;

· The material shelf has a program gradient electric heating function (except LGJ-10C), special aviation heating film, PLD control, built-in overheating protection, safe and reliable;

· Adopts imported compressor single-machine hybrid refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature and strong water capture capacity;

· Optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. The main power supply will be restored within 5 minutes, and the safety conditions will be automatically determined to restore the equipment to the current stage of operation.

·Effective shelf area: 0.1\ m^{2}
·Standard cold trap temperature: <= -68°C (no load, ambient temperature \le30°C)
· Limit cold trap temperature: <=-70°C (no load, ambient temperature \le25°C)
·Standard vacuum degree: <=5\mathsf{P a} (no load)
· Ultimate vacuum degree: <= 1Pa (no load)
· Cold trap cooling rate: 20°C to -40°Cs 20min (no load)
Vacuum pumping rate: standard atmospheric pressure drops to 5Pa ≤ 15min (no load)
·Maximum water capture: 5\mathsf{K g}
·Shelf size: diameter \Phi210mm
·Number of shelves: 4
· Shelf heating temperature control range: -40°C~+50°C (Except LGJ-10C)
·Main body dimensions (Lx\mathsf{W}x\mathsf{H}) 610mmx610mmx460mm
·Net Weight: 85kg
· Power supply: AC220V 50Hz
·Power:LGJ-10C1050W，LGJ-10E1200W
·Suitable ambient temperature: \le30°C

Capping device

Manifold device

Optional:

multi-manifold bottle hanging device, freeze-dried bottles (eggplant-shaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, vial capping machine,

eutectic point tester, inert gas filing port, imported vacuum pump, high-speed vacuum pump oil, stainless steel laboratory trolley.

LGJ-16C/D24C/D Freeze Dryer

Technical Feature :

· The control software system is Android system. The freeze-drying process is automatically controlled by programmable programs (optional). It can be switched to manual operation in real time to achieve full parameter control of the freeze-drying process. During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs. It can be monitored, tested, and maintained through a remote system (optional), supporting the construction of big data and smart laboratories.

· Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage interval is adjustable), standard record 100,0o0 times, data storage capacity can be recorded for 3 years (optionall, with USB serial port for mobile data storage;

· The product production has passed the ISO quality management system and the EU CE certification, and the control system human-machine interface complies with the NEMA (National Electrical Manufacturers Association)protectionregulations.

·The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature, shelf temperature in real time.Operation error alarm can provide instant information alarm and activelyprotectoperationwhentemperature andpressureare abnormal duringoperation.Light alarm(optional);

·When the equipment loses vacuum pressure at the end of the automatic freeze-drying operation or during theprocess,theequipmentwillalarmand automaticallyoperatetoprotectthematerials.Whenthecold trap temperatureishigherthan -50°C ,thevacuumpumpcannotbeturned ontoprevent the entry of watervapor and affect the normal operation of thevacuum pump. It has a vacuumpumpmaintenancereminderfunction;

·The materials are freeze-dried in situ. The internal fillet, surface roughness, shelf flatness and internal materials of the freeze-drying chamber meet or exceed the relevant national standards. The shelves can be disassembled,aresmooth,corrosion-resistant and easytoclean.

· The material shelf has a program gradient electric heating function, a special aviation heating film, PLD control, built-in overheating protection, safe and reliable; (Except LGJ-16C/24C)

· Adopting imported compressor single-unit hybrid refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, strong water capture capacity;

· The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. If the main power is restored within 5 minutes, the system will automatically determine the safety conditions and resume the operation of the equipment according to the currentstage.

·Standard pre-freezing chambertemperature: <=-50°C (no load, ambient temperature \le30°C)
·Extremepre-freezingchambertemperature: <=-55°C (no load, ambient temperature <=25°C)
·Standardcoldtraptemperature: <=-60°C (no load, ambient temperature \le30°C)
·Extreme cold trap temperature: <=-65°C (no load, ambient temperature \le25°C)
·Standardvacuumdegree: <=5\mathsf{P a} (no load)
·Extremevacuumdegree: <= 1Pa (no load)
· Shelf cooling rate: 20°C down to -40°Cs 60min (no load)
· Cold trap cooling rate: 20°C down to -40°Cs 20min (no load)
· Vacuum pumping rate: standard atmosphericpressuredownto 5Pa≤ 15min (no load)
·Shelf temperaturecontrolrange: -40°C~+70°C (Except LGJ-16C/24C)
·Power Supply:AC220V 50Hz
●Power:1800w
·Suitable ambient temperature: <=30°C

Optional:

multi-manifold bottle hanging device, freeze-dried bottles (eggplant-shaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, vial capping machine, imported vacuum pump, highspeedvacuumpumpoil.

LGJ-12F15F25C/E/F FreezeDryer

Technical Feature :

· The control software system is an Android system. The freeze-drying process is automatically controlled by a programmableprogram(optional). It canbeswitched tomanual operation inreal timeto achievefull parameter control of the freeze-drying process. During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs. It can be monitored, tested, and maintained through a remote system (optional), supporting the construction of big data and smart laboratories.

· Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage interval is adjustable), standard record 100,0o0 times, data storage capacity can be recorded for 3 years (optional), with USB serial port for mobile data storage;

· The product production has passed the ISO quality management system and the EU CE certification, and the control systemhuman-machineinterfacecomplieswith theNEMA(National Electrical Manufacturers Association)protectionregulations.

· The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature, shelf temperature in real time, and can query allhistorical records. Operation error alarm can provide instant information alarm and actively protect operation when temperature and pressure are abnormal during operation, light alarm (optional);

· When the automatic freeze-drying ends or the vacuum pressure of the equipment is lost during the process, theequipmentwillalarmand automaticallyoperatetoprotect thematerials.Whenthecold traptemperature is higher than -50°C thevacuumpumpcannot be turned on toprevent the entry of watervapor and affect the normal operation of the vacuum pump. It has a vacuum pump maintenance reminder function;

· The cold trap cavity and material rack are made of sanitary stainless steel. There is no coil in the cold trap, which is smooth, corrosion-resistant and easy to clean, and has the function of pre-freezing materials.

· The cold trap drying chamber is made of high-pressure and low-temperature resistant aviation organic glass material, covered with an explosion-proof film (optional), so that the entire freeze-drying process of the materialcanbeobserved;

· The material shelf has a program gradient electric heating function (except LGJ-25C, LGJ-12F/15F/25F is optional), special aviation heating flm, PLD control, built-in overheating protection, safe and reliable;

· Adopting imported compressor single-machine hybrid refrigeration technology (LGJ-12F/15F/25F models adopt dual compressor cascade refrigeration technology), with multiple protections such as over-high oil pressure, over-temperature, delayed start, etc., international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, and strong water capture capacity; ·With nrnaram-controlled alitomatic: defrnstina fu inctinn.

· The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. The main power supply will be restored within 5 minutes, and the safety conditions willbe automatically determined to restore the equipment to the current stage of operation.

Optional automatic drainage and exhaust, pipeline moisture detec · Optional automatic program-controlled re-pressure aeration backfilling system can reduce secondary contamination of samples. Nitrogen or inert gas can be quantitatively (optionally) backfilled. After freeze-drying, the vacuum pump stops and the re-pressure aeration starts automatically. The vacuum system is interlocked with the re-pressure aeration backfilling system to prevent the vacuum pump oil from backflowing and spraying into the cold trap and drying chamber to contaminate the freeze-dried materials.

·Effective shelf area: 0.25m^{2} ( LGJ-12F/15F 0.12\mathsf{m}^{2} /0.15\mathsf{m}^{2}
·Standard cold trap temperature: <=-62°C (no load, ambient temperature \le30°C) <=-83°C (LGJ-12F/15F/25F, no load, ambient temperature \le30°C)
·Extreme cold trap temperature: <=-65°C (no load, ambient temperature \le25°C) <=-86°C (LGJ-12F/15F/25F,noload,ambient temperature <=25°C)
·Standard vacuum degree: <=5\mathsf{P a} (no load)
· Ultimate vacuum degree: <= 1Pa (no load)
· Cold trap cooling rate: 20°C to -40°Cs 15min (no load)
· Vacuum pumping rate: standard atmosphericpressuredropsto5Pa <= 15min (no load)
·Maximum water capture capacity: 11\ K_{9} (LGJ-12F/15F 6 Kg)
· Shelf size: diameter \Phi300\;mm (LGJ-12F/15F diameter \Phi210mm)
·Shelf number: 4 layers (LGJ-12F/15F 5 layers/6 layers)
· Shelf heating temperature control range: -40°C~+50°C (Except LGJ-25C, LGJ-12F/15F/25F optional)
·External dimensions (Lx\mathsf{W}x\mathsf{H}) 640mmx590mmx845mm
●Power supply: AC220V 50Hz
·Power: LGJ-25C 1900W,LGJ-25E 2150W LGJ-12F/15F2100W，LGJ-25F2550W
· Suitable ambient temperature: <=30°C

12-manifold rack

Optional:

multi-manifold bottle hanging device, freeze-dried bottles (eggplant-shaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, vial capping machine, eutectic point tester, inert gas filling port, imported vacuum pump, high-speed vacuum pump oil

LGJ-50C/D80C/D Freeze Dryer

Technical Feature :

·The control software system is LINuX system. The freeze-drying process is automatically controlled by programmable programs and can be switched to manual operation in real time to achieve full parameter control of the freeze-drying process. During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs, with a storage program of >=100 and each program step of >=36 It reaizes multi-level management and can be monitored, tested, and maintained through the standard remote system. It supports the construction of big data and smart laboratories, and audit tracking.
· Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage record interval is adjustable), standard record 100,000 times, data storage capacity can be recorded for 3 years (optional), with USB serial port for mobile data storage;
· The product production has passed the ISO quality management system and the EU CE certification, and the control system human-machine interface complies with the NEMA (National Electrical Manufacturers Association) protection regulations.
· The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature, shelf temperature in real time, operation error alarm, and can provide instant information alarm and active protection operation when temperature and pressure are abnormal during operation, and light alarm (optional);
· The internal fillet, surface roughness, shelf flatness and internal materials of the freeze-drying chamber meet or exceed relevantnationalstandards;
·The material is freeze-dried in situ. The cold trap cavity and material tray are made of sanitary stainless steel. There is no coil in the cold trap. The shelves can be disassembled, which are smooth, corrosion-resistant and easy to clean. The shelf spacing can be freely adjusted by adjusting the number of shelf layers according to the height requirements of the material container. The freeze-drying area can be arbitrarily configured (the maximum effective freeze-drying area is 0.83\mathsf{m}^{2})
· The material shelf has a program gradient electric heating function, a special aviation heating film, PLD control, built-in overheating protection,safe and reliable;(Except LGJ-50C/80C)
· When the equipment loses vacuum pressure at the end of the automatic freeze-drying operation or during the process, the equipment will alarm and automatically operate to protect the materials. When the cold trap temperature is higher than -50°C the vacuum pump cannot be turned on to prevent the entry of water vapor and affect the normal operation of the vacuum pump.It has a vacuum pump maintenance reminder function;
· The external cold trap improves the water capture capacity of the equipment, reduces the interference of the cold trap temperature on the material during the freeze-drying process, ensures the consistency of the freeze-drying quality of the material, improves the freeze-drying efficiency, and reduces energy loss;
· Adopting imported compressor single-machine hybrid refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, strong water capture capacity.
· Automatic defrosting function.
· The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. If the main power is restored within 5 minutes, the system will automatically determine the safety conditions and resume the operation of the equipment according to the current stage.
· Optional automatic drainage and exhaust, pipeline moisture detection;
· Automatic re-pressure gas injection system: reduces secondary contamination of samples and can quantitatively (optionally) backil nitrogen or inert gas.
· Provide clean room installation solutions.
● Optional vacuum adjustment function;
· The vacuum degree is fully automaticaly controlled, and the vacuum degree adjustment function is optional;:
· Optional offine eutectic point test function to better optimize the sample sublimation process;
· Optional host computer control
·Standard cold traptemperature: \le-70°C (no load, ambient temperature \le30°C)
·Extreme cold trap temperature: \le-75°C (no load, ambient temperature \le25°C)
·Standard pre-freezing room temperature: <=-55°C (no load, ambient temperature \le30°C)
·Extremepre-freezingroomtemperature: <=-61°C (noload,ambienttemperature \le25°C)
·Standard vacuum degree: <= 5Pa (no load)
·Extremevacuumdegree: <=1 \mathsf{P a} (no load)
·Pre-freezing room cooling rate: 20°C downto -40°Cs 60min (no load)
·Cold trap cooling rate: 20°C down to -40°Cs 20min (no load)
·Vacuum pumping rate: standard atmospheric pressure down to 5Pas 15min (no load)
·Shelf temperature control range: -40°C~+70°C (Except LGJ-50C/80C)
·Power requirements: AC380V50Hzthree-phasefive-wireorAC220V50Hz
●Total power:4000w
·Suitable ambient temperature: <=30°C

Optional:

multi-manifold bottle hanging device, freeze-dried bottles (eggplant-shaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, vial capping machine, imported vacuum pump, highspeed vacuumpump oil.

LGJ-15E/22E/30E Freeze Dryer

Technical Feature :

· The control software system is LINUX system. The freeze-drying process is automatically controlled by programmable programs and can be switched to manual operation in real time to achieve full parameter control of the freeze-drying process. During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs, with a storage program of >=\uparrow00 (can be increased to 600 according to customer needs), and each program has >=36 steps,realizing multi-level management. It can be monitored, tested, and maintained through the standard remote system, supporting the construction of big data and smart laboratories, and audit tracking.

·Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage record interval is adjustable), standard record 100,0o0 times, data storage capacity can be recorded for3years (optional), with USB serial port for mobile data storage;

· The product production has passed the ISO quality management system and the EU CE certification, and the control systemhuman-machine interfacecomplieswith the NEMA(National Electrical Manufacturers Association)protectionregulations.

· The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature, shelf temperature in real time. The operation error alarm can provide instant information alarm and actively protect the operation when abnormal temperature and pressure occur during operation. Adjustable sound and light alarm (optional), emergency stop switch (optional;

· It has the function of alarming and automatically operating to protect materials when the equipment loses vacuum pressure at the end of automatic freeze-drying or during the process, and has thefunction of prompting maintenanceof vacuumpump;

·The internal fllet, surface roughness, shelf flatness and internal materials of the freeze-drying chamber all meet pharmaceutical standards,and aresmooth,corrosion-resistant and easy to clean.

· The freeze-drying automatic control system adopts PID control for both heating and cooling during the freezedrying process, which can automatically realize repeated pre-freezing, quick freezing and slow freezing of materials;

· Special mechanical process manufacturing ensures that the shelf surface is flat and the internal circulation channel has the same diameter, so that the intermediate medium (low viscosity silicone oil, 25{^\circC} 5cSt) circulates evenly and steadily in the shelf, with uniform temperature and good heat and cold conduction, which improves the freeze-drying efficiency.

· Adopting imported compressor double-machine cascade refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, strong water capture capacity;

· The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. If the main power is restored within 5 minutes, the system will automatically determine the safety conditions and resume the operation of the equipment according to the currentstage.

· Optional automatic drainage and pipeline moisture detection.

·Optional plugging mode: manual or electric;

·Provide clean room installation solutions · Optional host computer control

·Standard cold trap temperature: \le-75°C (no load, ambient temperature \le30°C)
·Extremecold traptemperature: \le-78°C (no load, ambient temperature <=25°C)
·Standardvacuumdegree: <=5\mathsf{P a} (no load)
·Extreme vacuum degree: ≤ 1Pa (no load)
· Shelf cooling rate: 20°C to -40°Cs 60min (no load)
·Cold trap cooling rate: 20°C to -40°Cs 20min (no load)
· Vacuum pumping rate: standard atmospheric pressure drops to 5Pa ≤ 15min (no load)
·Maximum water capture capacity: 6\mathsf{K g}
·Shelf size (length x width): 325mm{x}245mm
·Shelf temperature range: -50°C~+70°C
·External dimensions( Lx\mathsf{W}x\mathsf{H} 680mmx700mmx1288mm
·Power supply requirement: AC380V 50Hz three-phasefive-wire orAC220V50Hz
·Total power: 3300w
·Suitable ambienttemperature: <=30°C

Optional:

multi-manifold bottle hanging device, freeze-dried bottles (eggplant-shaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, vial capping machine, imported vacuum pump, highspeed vacuumpump oil.

LGJ-12G/20G/30G/40G/20H/30H/40H FreezeDryer

Technical Feature :

·The control software system is LINuX system. The freeze-drying process is automatically controlled by programmable programs and can be switched to manual operation in real time to achieve full parameter control of the freeze-drying process.During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs, with a storage program off >=100 (can be increased to 600 according to customer needs), and each program has >=36 steps, realizing multi-level management. It can be monitored, tested and maintained through the standard remote system, supporting the construction of big data and smart laboratories, and audit tracking.
·Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage record interval is adjustable), standard record 100,000 times, data storage capacity can be recorded for 3 years (optional), with USB serial port for mobile data storage;
· The product production has passed the ISO quality management system and the EU CE certification, and the control system humanmachine interface complies with the NEMA (National Electrical Manufacturers Association) protection regulations.
· The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature, shelf temperature in real time. The operation error alarm can provide instant information alarm and actively protect the operation when the temperature and pressure are abnormal during operation. Adjustable sound and light alarm (optional) and emergency stop switch (optional;
· When the vacuum pressure of the equipment is lost at the end of the automatic freeze-drying operation or during the process, the equipment will alarm and automatically operate to protect the materials.It also has the function of prompting the maintenance of the vacuumpump.
●In-situ freeze drying, the internal fllet, surface roughness, shelflatness, and internal materials of the freeze drying chamber all meet pharmaceutical standards, are smooth, corrosion-resistant and easy to clean. LGj-20H/30H/40H are highly similar to the design principle and manufacturing form of production machines;
·The freeze-drying automatic control system adopts PiD control for both heating and cooling during the freeze-drying process, which can automatically realize repeated pre-freezing, quick freezing and slow freezing of materials;
·Special mechanical process manufacturing ensures that the shelf surface is flat and the internal circulation channel has the same diameter, so that the intermediate medium (low viscosity silicone oil, 25{^\circC} 5cSt) circulates evenly and steadily in the shelf, with uniform temperature and good heat and cold conduction, thus improving freeze-drying eficiency;
· The external cold trap improves the water capture capacity of the equipment,reduces the interference of the cold trap temperature on the material during the freeze-drying process,ensures the consistency of the freeze-drying quality of the material and the stability of the experimental data,improvesthefreeze-dryingefficiency,andreducesenergyloss.
·Adopt imported compressor double-machine cascade refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, strong water capture capacity.
· Optional butterfly valve to close the pipeline between the freeze drying chamber and the water collection chamber before freeze drying and after freeze drying, which can ensure that materials can be loaded and unloaded and products can be pre-frozen in a clean environment. After freeze drying, it can be measured and controlled to determine whether the freeze drying of materials is completed (optional), thereby improving the freeze drying efficiency of the equipment.
● Automatic defrosting function;
· The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. If the main power is restored within 5 minutes, the system will automatically determine the safety conditions and resume the operation of the equipment accordling to the current stage.
· Optional automatic drainage and pipeline moisture detection.
· Automatic re-pressure gas injection system: Reduces secondary contamination of samples and can quantitatively (optionally) backill nitrogen or inert gas.
· Optional plugging method: manual or electric
● Provide clean room installation solutions.
· Optional vacuum adjustment function, automatic and precise control of vacuum degree throughout the process (5Pa \~ 80Pa, ±1Pa).
· Optional eutectic point test function to better optimize the sample sublimation process.
· Optional host computer control
· Optional freeze-drying endpoint test
·Standard cold traptemperature: <= -83°C (no load, ambient temperature <=30°C)
·Extreme cold trap temperature: -86°C (noload,ambient temperature <=25°C)
·Standardvacuum degree: <=5\mathsf{P a} (no load)
·Extremevacuumdegree: \le 1Pa (no load)
·Shelf cooling rate: 20°C to -40°Cs 60min (no load)
·Cold trap cooling rate: 20°C to -40°Cs 20min (no load)
·Vacuum pumping rate: standard atmospheric pressure drops to 5Pas 15min (no load)
·Maximum water capture capacity: 8Kg (LGJ-20H/30H/40H:10Kg,LGJ-12G:4Kg)
·Shelf size (length x width): 335mmx300mm(LGJ-12G:325mmx385mm)
·Shelf temperaturecontrolrange: -50°C~+70°C
·External dimensions( Lx Wx H G type:700mmx800mmx1550mm H type:1200mmx680mmx1250mm (LGJ-12G:930mmx660mmx740mm)
·Power supply requirements:AC380V 50Hz three-phase five-wire or AC220V 50Hz (LGJ-12G: AC220V 50Hz)
●Total power:3300W (LGJ-12G:2100W)
·Suitable ambient temperature: <=30°C

Optional:

multi-manifold bottle hanging device, freeze-dried bottles (eggplantshaped bottles and wide-mouth bottles), ampoule freeze-dried rack, ampoule sealer, vial capping machine, imported vacuum pump, high-speed vacuum pump oil.

LGJ-12G

LGJ-20G/30G/40G
LGJ-20H/30H/40H

LGJ-50E/50H/80E/100E/120E FreezeDryer

Technical Feature :

·The control software system is LINuX system.The freeze-dryingprocess is automatically controlled byprogrammable programs and can be switched to manual operation in real time to achieve fullparameter control of the freeze-drying process.During operation,the system automatically monitors,detects,and records and stores relevant data.lIt can store multiple fixed or customprograms,with a storage program of =100 (canbe increased to 600 according to customer needs),andeachprogramhas >=36 steps, realizing multi-level management. It can be monitored, tested, and maintained through the standard remote system, supporting the construction of big data and smart laboratories, and audit tracking.

·Continuouslyrecordreal-timedata,drawfreeze-drying curve,storedata onceeveryminute(storagerecord interval is adjustable), standard record 100,0o0 times,data storage capacity can berecorded for3 years (optional),with USB serial portfordatamobilestorage.

·The product production has passed the ISO quality management system and the EU CE certification, and the control system human-machine interface complies with the NEMA (National Electrical ManufacturersAssociation) protection regulations.

·The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature,shelf temperature inreal time.The operationerroralarmcanprovide instant information alarm and actively protect the operation when the temperature and pressure are abnormal during operation.Adjustable sound and light alarm (optional) and emergency stop switch (optional;

· It has the function of alarming and automatically operating to protect materials when the automatic freeze-drying ends or the equipment loses vacuum pressure during the process. lt also has the function of reminding the maintenance of the vacuumpump.

· The design principle and manufacturing form are highly similar to those of production machines, and the component materials and surface treatment meet or exceed relevant national and industry regulations.

· The freeze-drying automatic control system adopts PID control for both heating and cooling during the freeze-drying process,which can automatically achieve repeated pre-freezing,quick freezing and slow freezing of materials at multiple rates;

·Special mechanical process manufacturing ensures that the shelf surface is flat and the internal circulation channel has the samediameter,sothat the intermediatemedium(lowviscositysiliconeoil, 25% 5cSt)circulatesevenlyandsteadilyinthe shelf, with uniform temperature and good heat and cold conduction, thus improving freeze-drying efficiency.

·The external cold trap improves thewatercapture capacity of the equipment,reduces the interference of the cold trap temperature on the material during the freeze-drying process, ensures the consistency of the freeze-drying quality of the materialandthestabilityoftheexperimentaldata,improvesthefreeze-dryingefficiencyandreducesenergyloss.

·Adopting imported compressor double-machine cascade refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, strong water capture capacity.

· The butterfly valve that closes the pipeline between the freeze-drying chamber and the water collection chamber before and after freeze-drying can ensure that the materials are loaded and unloaded and the products are pre-frozen in a clean environment. After freeze-drying, the freeze-drying of the materials can be measured and controlled to determine whether it is finished (optional), which improves the freeze-drying efficiency of the equipment.

● The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. If the main power is restored within 5 minutes, the system will automatically determine the safety conditions and resume the operation of the equipment according to the current stage.

Optionalvacuumadjustmentfunction,automaticand precise control of vacuum degree throughout the process (5Pa\~80Pa, ±1\left|P\right⟩
·Optional eutectic point test function to better optimize the sample sublimation process;
·Optional hostcomputer control
· Optional freeze-drying endpoint test.

Optional:

imported vacuum pump, high-speed vacuum pump oil

·Standardcoldtraptemperature: <=-80°C (no load,ambient temperature≤ 30°C) \le-75°C (no load, ambient temperature \le30°C , LGJ-120E)
·Extreme cold traptemperature: <=-83°C (no load, ambient temperature <= 25°C) <=-80°C (no load, ambient temperature <=25°C LGJ-100E/120E)
·Standard vacuum degree: <=10\mathsf{P a} (no load); <= 5Pa (LGJ-50E/50H)
·Extremevacuum degree: <= 1Pa (no load)
·Shelf cooling rate: 20°C down to -40°Cs 60min (no load)
· Cold trap cooling rate: 20°C downto -40°Cs 30min (no load)
·Vacuum pumping rate: standard atmospheric pressure down to 10Pa \le 20min (no load) Standard atmosphericpressuredropsto 5\mathsf{P a}<=20\mathsf{m i n} (no load) (LGJ-50E/50H)
·Shelf temperature control range: -50°C~+70°C
·Powersupplyrequirements:AC380v 50\mathsf{H}z three-phase five-wire system
·Suitable ambient temperature: \le30°C

LGJ-200B/200C/300B/500B FreezeDryer

Technical Feature :

· The control software system is LINUX system. The freeze-drying process is automatically controlled by programmable programs and can be switched to manual operation in real time to achieve full parameter control of the freeze-drying process. During operation, the system automatically monitors, detects, and records and stores relevant data. It can store multiple fixed or custom programs, with a storage program of >=100 (can be increased to 6o0 according to customer needs), and each program has >=36 steps,realizing multi-level management. It can be monitored, tested and maintained through the standard remote system, supporting the construction of big data and smart laboratories, and audit tracking;

· Continuously record real-time data, draw freeze-drying curve, store data once every minute (storage record interval is adjustable), standard record 100,0o0 times, data storage capacity can be recorded for 3 years (optional), with USB serial port for data mobile storage;

· The product production has passed the ISO quality management system and the EU CE certification, and the control system human-machine interface complies with the NEMA (National Electrical Manufacturers Association)protectionregulations.

· The system is equipped with various sensors to record and display vacuum degree, cold trap temperature, material temperature, shelf temperature in real time. The operation error alarm can provide instant information alarm and actively protect the operation when the temperature and pressure are abnormal during operation. Adjustable sound and light alarm (optional) and emergency stop switch (optional);

· It has the function of alarming and automatically operating to protect materials when the automatic freezedrying ends or the equipment loses vacuum pressure during the process. It also has the function of reminding the maintenance of the vacuum pump.

· Component materials and surface treatment meet or exceed relevant national and industry regulations; · The freeze-drying automatic control system adopts PID control for both heating and cooling during the freezedrying process, which can automatically achieve repeated pre-freezing, quick freezing and slow freezing of materials at multiple rates;

·Special mechanical processmanufacturing ensuresthat theshelf surfaceisflat and the internal circulation channel has the same diameter, so that the intermediate medium (lowviscosity silicone oil, 25{^\circC} 5cSt circulatesevenly andsteadilyintheshelf,withuniformtemperature and good heat andcold conduction, thus improving thefreeze-drying eficiency.

·Adopt imported compressor refrigeration technology, international standard green environmental protection refrigerant, rapid refrigeration, low cold trap temperature, strong water capture capacity;

· The valve of the pipeline between the freeze-drying chamber and the water collection chamber is closed before the freeze-drying preparation and after the freeze-drying is completed, which can ensure that the materials are loaded and unloaded and the products are pre-frozen in a clean environment. After the freeze-drying, the freeze-drying of the materials can be measured and controlled to determine whether it is finished (optional), thereby improving the freeze-drying efficiency of the equipment;

· Automatic defrost function

· The optional UPS uninterruptible power supply can provide the control system with 20 minutes of power supply after a sudden power outage. If the main power is restored within 5 minutes, the system will automatically determine the safety conditions and resume the operation of the equipment according to the currentstage.

· Re-pressurization gas injection system: Reduce secondary contamination of samples, backil with nitrogen or inert gas.

·Pressing method:electric
·Providecleanroominstallationsolutions
·Optional vacuumadjustmentfunction,automatic andprecisecontrolofvacuumdegree (5Pa \~ 80Pa, ±1 \mathsf{P a})
·Optional eutecticpoint test in place function to betteroptimize thesamplesublimationprocess;
· Optional host computer control.
· Optional cleaning in place and sterilization in place functions.
· Optional freeze-drying endpoint test.

Optional:

imported vacuum pump, high-speed vacuum pump oil

·Standard cold trap temperature: <=-70°C (no load, ambient temperature \le30°C)
·Standard vacuum degree: <=10\mathsf{P a} (no load)
· Shelf cooling rate: 20°C to -40°Cs 60min (no load)
· Cold trap cooling rate: 20°C to -40°Cs 30min (no load)
· Vacuum pumping rate: standard atmospheric pressure drops to 10Pa <= 30min (no load)
· Shelf layer spacing: 100mm (LGJ-200C 70mm)
·Shelf temperature control range: -50°C~+70°C
· Power supply requirements: AC380V 50Hz three-phase five-wire system
·Suitable ambient temperature: <=30°C Foring Science Instrument Technology Development ( Beijing ) Co.,Ltd.
Four Ring Science Instrument Technology Development(Hebei) Co., Ltd.

Address: 1005, Unit 2, 12th Floor, Building 1, No. 3 Rongjingdong Street, Bejing Economic and Technological Development Zone, Beijing